Microscopes

Life Sciences Research AFMs

Providing unique insights into life sciences research with previously inaccessible data, including physical structure, biochemical interactions, and mechanical properties

Advanced Imaging

Bruker has been helping biologists discover, understand, publish, and advance their knowledge of biological systems ever since our introduction of TappingMode™ expanded AFM use into life sciences research. In addition to general-purpose BioAFM systems specifically designed for life sciences research and suitable for a broad range of applications, Bruker offers a variety of specialized systems utilizing proprietary AFM features. These instruments include BioAFMs for high-speed imaging to support the investigation of dynamic processes; BioAFMs optimized for the investigation of cells and tissues, even uneven or highly corrugated samples; and BioAFMs for single-molecule applications ranging from single-molecule property characterization to the investigation of conformational changes at the single-molecule level, intra-molecular dynamics, and single-molecule spectroscopy (SMFS). 

 

These instruments deliver the highest quality results for quantitative live-cell mechanical property mapping, highest resolution molecular and cellular imaging, and fast scanning of dynamic biological processes, as well as seamless integration of AFM with advanced optical microscopy techniques.

Products

Find the Best BioAFM for Your Application

Accessories and System Options

Customize Your BioAFM System


Accessories to extend your BioAFM capabilities  

Bruker offers an extensive range of BioAFM system add-ons, accessories, and modes to deliver maximum experimental and sample control, superior versatility, and enhanced useability. These options extend the range of applications and experiments supported by Bruker BioAFMs far beyond what is possible with any other BioAFM system on the market today.

Available options include optical systems/accessories, electrochemistry solutions, electrical sample characterization, environmental control options, software modules, temperature control, acoustic and vibration isolation solutions, and more.
 

Browse our online accessories database or download our accessories handbook to learn more.

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BioAFM FAQs

Frequently Asked Questions

BioAFM is an increasingly important tool in biological and biomedical studies due to its very high resolution and the possibility of conducting experiments with live cells under physiologically relevant and ambient conditions, even in liquid. BioAFM also provides nanometer-resolution surface mapping for many mechanical and electrical properties, such as elasticity, stiffness, conductivity and surface potential. Bruker BioAFM technology is enabling life science researchers to investigate how these properties impact on cellular functions, including communication, signaling, cell division and differentiation, and even tumor metastasis and infection.

Applications

What Can You Do With a BioAFM?

Resources

Learn More About Our BioAFM Technology

Bruker has deep experience and expertise supporting life science and biophysics research in the fields of cell mechanics and adhesion, mechanobiology, cell-cell and cell-surface interactions, cell dynamics, and cell morphology.

We are eager to share this knowledge with the larger research community. Be sure to explore our extensive offering of BioAFM resources, below.

Contact us to discuss your specific application requirements and measurement needs with a BioAFM expert.

Watch Our BioAFM Webinars

Our webinars cover best practices, introduce new products, provide quick solutions to tricky questions, and offer ideas for new applications, modes, or techniques.

Service and Support

How Can We Help?

Bruker partners with our customers to solve real-world application issues. We develop next-generation technologies and help customers select the right system and accessories. This partnership continues through training and extended service, long after the tools are sold.

Our highly trained team of support engineers, application scientists and subject-matter experts are wholly dedicated to maximizing your productivity with system service and upgrades, as well as application support and training.

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